Hydroxypyridinone derivatives, metal complexes thereof and the use thereof for preparing conjugates with biomolecules
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United States of America Patent
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Issued Date -
Jan 4, 2007
app pub date -
Dec 20, 2005
filing date -
Dec 23, 2004
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Abstract
The invention relates to hydroxypyridinone derivatives, their metal complexes, their preparation and their use for preparing conjugates with biomolecules. The conjugates are suitable as contrast agents in NMR diagnosis. A high relaxivity is achieved and the NMRD maximum is raised through a specific design of the ligands.
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