2-Aminopyrimidine derivatives as raf kinase inhibitors
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United States of America Patent
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Issued Date -
Dec 28, 2006
app pub date -
Jun 11, 2004
filing date -
Jun 13, 2003
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Abandoned
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Abstract
This application discloses compounds that inhibit Raf kinase having the formula (I), wherein R.sub.1 is a phenyl radical or a heteroaryl radical; and R.sub.2 is a phenyl radical; or an N-oxide or a pharmaceutically acceptable salt thereof. The compounds are useful for the treatment of proliferative diseases, such as cancer.
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