Addition of transgenes into adenoviral vectors
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United States of America Patent
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Issued Date -
Dec 28, 2006
app pub date -
Jul 15, 2005
filing date -
Jul 22, 2004
priority date (Note) -
Abandoned
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Abstract
Adenoviral vectors are provided that contain a transgene inserted in the viral genome at a novel site such that one or more of native processing, regulatory signals or heterologous transcription signals such as branch point sites, splice acceptor sites, internal ribosome entry sites, self-processing cleavage sites and/or polyA signals contribute to transgene expression.
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