Conjugates of hydroxypyridinone derivative metal complexes with biomolecules and their use for MRI diagnosis
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United States of America Patent
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Issued Date -
Dec 28, 2006
app pub date -
Dec 20, 2005
filing date -
Dec 23, 2004
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Abandoned
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Abstract
The invention relates to conjugates of hydroxypyridinone derivative metal complexes and to their preparation. The conjugates are suitable as contrast agents in NMR diagnosis. A high relaxivity is achieved and the NMRD maximum is raised through a specific design of the ligands.
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