Methods and compositions for treating B cell cancer
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United States of America Patent
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app pub date -
May 11, 2006
filing date -
Nov 12, 2003
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Abandoned
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Abstract
Disclosed are methods for killing or retarding the growth of a B cell cancer cell, by contacting the cell with a FRIL family member molecule. Also disclosed are methods for determining if a B cell cancer is sensitive to a FRIL family member molecule, or if a B cell cancer patient will benefit from treatment with a FRIL family member molecule, by contacting a B cell cancer cell with the FRIL family member molecule and determining if growth of the cell is retarded. In addition, methods for treating a B cell cancer patient are disclosed, as well as compositions comprising a FRIL family member molecule and a chemotherapeutic, radiotherapeutic, or agent that selectively kills B cells. Also disclosed are methods for locating a B cell cancer in a patient by administering a detectably labeled FRIL family member molecule to the patient and detecting the label.
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