Process for the preparation of valsartan and its intermediates
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United States of America Patent
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Issued Date -
Dec 14, 2006
app pub date -
Apr 18, 2006
filing date -
Apr 19, 2005
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Abstract
The present invention relates to an improved process for the preparation of valsartan and its intermediates in substantially pure enantiomeric form. In particular, the present invention provides a process for preparing benzyl valsartan intermediate substantially free of organotin impurities. The valsartan produced from such benzyl valsartan intermediate requires significantly lower catalyst loading and has superior purity.
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