Pharmaceutical composition useful for the treatment of hepatocellular carcinoma

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United States of America Patent

APP PUB NO 20060280817A1
SERIAL NO

11440790

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Abstract

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The present invention relates to anticancer activity against hepatocellular carcinoma of an extract and fraction isolated from flowers of Butea monosperma. Particularly, this invention relates to anticancer activity against hepatocellular carcinoma of a composition containing markered flavonoid glycosides such as butrin and isobutrin in the range of 2 to 9% by weight, isolated from the flowers of Butea monosperma by extracting the flowers with polar solvent like ethanol, methanol, aqueous ethanol or water, removing fatty non-polar constituents by triturating the extract with solvents such as ethylene chloride, methylene chloride, chloroform or ethyl acetate, suspending the residue in water, extracting with n-butanol and freeze drying the aqueous part.

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Patent Owner(s)

Patent OwnerAddress
COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHANUSANDHAN BHAWAN 2 RAFI MARG NEW DELHI DELHI 110 001
INTERNATIONAL CENTRE FOR GENETIC ENGINEERING & BIOTECHNOLOGYARUNA ASAF ALI MARG NEW DELHI 110067

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baleshwar, Jammu, IN 1 1
Gupta, Bishan Datt Jammu, IN 18 29
Kapahi, Bal Krishan Jammu, IN 13 42
Kumar, Vijay New Delhi, IN 224 3329
Mathan, Ganeshan New Delhi, IN 1 1
Mondhe, Dilip Manikrao Jammu, IN 9 24
Muthiah, Shanmugavel Jammu, IN 2 4
Qazi, Ghulam Nabi Jammu, IN 46 91
Saxena, Ajit Kumar Jammu, IN 15 17

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