Electrochemical detection of DNA binding
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United States of America Patent
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Issued Date -
Dec 7, 2006
app pub date -
Dec 22, 2005
filing date -
Mar 5, 2003
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Abandoned
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Abstract
In one aspect, the invention provides methods and apparatus for detecting a protein binding to a nucleic acid by measuring the impedence of a nucleic acid layer on an electrode, for example by AC impedance spectroscopy. In one embodiment, such methods may for example be used to detect a mismatch in a nucleic acid duplex.
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