Preventive or remedy for inflammatory bowel diseases containing anti-cd81 antibody as the active ingredient
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United States of America Patent
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Issued Date -
Dec 7, 2006
app pub date -
Aug 25, 2004
filing date -
Aug 28, 2003
priority date (Note) -
Abandoned
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Abstract
It is possible to use a screening system using the inhibition of CD81 gene expression, the inhibition of CD81 expression or the inhibition of its function (activity) as an indication in searching for a drug for preventing, ameliorating or treating IBD. Also, anti-CD81 antibody is highly efficacious as the active ingredient of a drug for preventing, ameliorating or treating IBD. Further, it is possible to use a polynucleotide having at least 15 consecutive bases in the base sequence of CD81 gene and/or a polynucleotide complementary to the above polynucleotide as a disease marker for IBD.
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