Potent and specific immunoproteasome inhibitors
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United States of America Patent
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Sep 15, 2009
Grant Date -
Oct 26, 2006
app pub date -
Mar 13, 2006
filing date -
Mar 11, 2005
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Compounds and methods of selectively inhibiting an immunoproteasome are described. Also described are methods of treating a cancer, an inflammation, and/or an autoimmune disease and methods of suppressing endogenous antigenic peptide generation by administering to a subject in need of treatment thereof a therapeutic amount of an immunoproteasome specific inhibitor.
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