Beta-secretase inhibitors and methods of use
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
N/A
Issued Date -
Oct 19, 2006
app pub date -
Oct 23, 2002
filing date -
Oct 23, 2001
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
Compounds inhibit memapsin 2 .beta.-secretase activity and selectively inhibit memapsin 2 .beta.-secretase activity relative to memapsin 1 .beta.-secretase activity. The compounds are employed in methods to inhibit memapsin 2 .beta.-secretase activity, in the treatment of Alzheimer's disease, in the inhibition of hydrolysis of a .beta.-secretase site of a .beta.-amyloid precursor protein and to decrease .beta.-amyloid protein in in vitro samples and in mammals. Proteins of memapsin 2 associated with compounds of the invention are crystallized.
First Claim
Family
International Classification(s)
- [Classification Symbol]
- [Patents Count]
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully