Biomolecule detecting apparatus and biomolecule detecting method employing the same

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United States of America Patent

APP PUB NO 20060223170A1
SERIAL NO

11329086

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A biomolecule detecting element capable of easily immobilizing a detecting probe and being used in a simple manner without requiring a dark box and the like. A biomolecule detecting probe is immobilized on the surface of a conductive electrode of an insulated gate field effect transistor, the conductive electrode being formed on the surface of a gate insulating material between a source and a drain. Portions other than the conductive electrode are covered with a light-shielding member so as to eliminate the influence of light. During measurement, the conductive electrode having a biomolecule detecting probe immobilized on the surface thereof and a reference electrode are disposed in a buffer solution in a measurement cell. A rectangular wave is applied to the reference electrode from a power supply, and a response waveform that changes before and after the binding of a measurement target, such as DNA or protein contained in the buffer solution, to the biomolecule detecting probe, namely, a change in the value of current that flows between the source and the drain, is detected.

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Patent Owner(s)

Patent OwnerAddress
HITACHI LTDTOKYO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ishige, Yu Tokyo, JP 24 364
Kamahori, Masao Kokubunji, JP 53 2087
Shimoda, Maki Hino, JP 11 215

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