Substituted alkyl-pyridazinones for the treatment of memory and learning malfunctions

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United States of America Patent

APP PUB NO 20060211703A1
SERIAL NO

10535039

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Abstract

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The compounds of the general Formula I, wherein R.sup.1 stands for hydrogen or lower alkyl; one of symbols X and Y stands for hydrogen or halogen and the other represents a group of the general Formula II, R.sup.2 is hydrogen or lower alkyl; n is 1, 2 or 3; R.sup.3 is hydrogen, lower alkyl or aryl-lower alkyl; Z is -0-; or R.sup.3 and Z together with the intermediate atoms form piperazino ring; Q and W independently from each other stands for --CH.dbd. or --N.dbd.; and R.sup.4, R.sup.5 and R.sup.6 can be the same or different and stand for hydrogen, halogen, trifluoromethyl or lower alkoxy; or R.sup.4 and R.sup.5 together form an ethylenedioxy group) and pharmaceutically acceptable salts thereof can be used for the treatment or prophylaxis of malfunctions of memory and/or cognitive decline or prevention of decline of learning abilities.

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Patent Owner(s)

Patent OwnerAddress
EGIS GYOGYSZERGYAR RTKERESZTURI UT 30-38 H-1106 BUDAPEST

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barkoczy, Jozsef Budapest, JP 45 669
Egyed, Andras Budapest, HU 22 95
Gacsalyi, Istvan Budapest, HU 41 127
Harsing, Laszlo Gabor Budapest, HU 15 4
Kompagne, Hajnalka Budapest, HU 6 2
Kotay, Nagy Peter Vac, HU 12 45
Levay, Gyorgy Budakeszi, HU 19 90
Leveleki, Csilla Budapest, HU 12 5
Marko, Bernadett Budapest, HU 2 0
Miklosne, Koivacs Aniko Budapest, HU 1 0
Schmidt, Eva Budapest, HU 22 102
Simig, Gyula Budapest, HU 75 181
Szenasi, Gabor Budapest, HU 17 51
Wellmann, Janos Budapest, HU 7 83

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