Enzymatic method of making ethyl 3-hydroxy-3-phenylpropionate and their esters
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United States of America Patent
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Issued Date -
Sep 14, 2006
app pub date -
Feb 5, 2004
filing date -
Feb 6, 2003
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Abandoned
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Abstract
The present invention provides a new process for the preparation of optically active ethyl 3-hydroxy-3-phenylpropionate and their esters by enzymatic method. More particularly, the racemic ethyl 3-hydroxy-3-phenylpropionate is converted to optically active ethyl 3-hydroxy-3-phenylpropionate and their esters by enzymatic reaction with acylating agent. This invention may be employed for the synthesis of individual enantiomers of ethyl 3-hydroxy-3-phenylpropionate.
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