Skin ulcer preventive curative agent containing human recombinant hgf
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United States of America Patent
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Issued Date -
Sep 7, 2006
app pub date -
Aug 27, 2004
filing date -
Sep 3, 2003
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Abandoned
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Abstract
A neovascularization promoting composition, a granulation formation-promoting composition and a preventive or curative composition for skin ulcer, comprising a human recombinant HGF wherein five amino acid residues are deleted in the first Kringle domain thereof. The provided compositions of the present invention are useful as a drug capable of promoting granulation formation and neovascularization and being effective in tissue restoration, especially as a preventive and curative agent for skin ulcer.
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