Compositions and methods for treating tissue ischemia
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United States of America Patent
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app pub date -
Dec 28, 2005
filing date -
Jun 30, 2003
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Abstract
The present invention generally provides methods for preventing or treating tissue ischemia using CXCR4 antagonists. In one embodiment, the methods include administering to a mammal a therapeutically effective amount of a particular bicylic polyamine to elevate peripheral blood EPCs. The invention has a wide spectrum of applications including reducing or eliminating tissue ishemica associated with a myocardial infarct (heart attack).
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