Process for the preparation of dihydroxy esters and derivatives thereof

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United States of America Patent

PATENT NO 7416865
APP PUB NO 20060194297A1
SERIAL NO

11412047

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Abstract

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A process is provided for the preparation of a compound of formula (1) ##STR00001## wherein R and R' represent optionally substituted hydrocarbyl groups and X represents a hydrocarbyl linking group. The process comprises either the stereoselective reduction of the keto group in a dihydroxy keto precursor followed by selective esterification of a primary hydroxy, or selective esterification of a primary hydroxy of a dihydroxy keto precursor followed by stereoselective reduction of the keto group.

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Patent Owner(s)

Patent OwnerAddress
ASTRAZENECA UK LIMITED1 FRANCIS CRICK AVENUE CAMBRIDGE BIOMEDICAL CAMPUS CAMBRIDGE CB2 0AA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blacker, Andrew John Huddersfield, GB 19 162
Holt, Robert Antony Billingham, GB 11 41
Reeve, Christopher David Billingham, GB 8 113

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