Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics
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United States of America Patent
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Issued Date -
Aug 31, 2006
app pub date -
Sep 22, 2005
filing date -
Mar 5, 2004
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Abandoned
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Abstract
The present invention provides materials and methods to treat immune disease in which cytokines are involved in pathogenesis. The materials and methods of the present invention are useful in the treatment of autoimmune diseases. The materials and methods of the present invention are directed to nucleic acid ligands capable of binding to human IL-23 and/or human IL-12 cytokines and thus modulate their biological activity and are useful as therapeutic agents in immune, auto-immune and cancer therapeutics.
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