Methods and compositions for colorimetrically assessing peptide characteristics

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United States of America Patent

APP PUB NO 20060188874A1
SERIAL NO

11317871

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Abstract

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Methodologies and compositions useful for calorimetrically assessing peptide characteristics. By way of example, the methodologies can be used to qualitatively and quantitatively assess the degree to which a peptide sample incorporates beta sheet content. The colorimetric information also information is useful to predict solubility, formulating, and other peptide characteristics impacted by beta sheet aggregation. The methodologies can also be practiced for quality control during peptide manufacture. The methodologies can be practiced to determine whether it might be desirable to subject a peptide sample to a deaggregation treatment.

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Patent Owner(s)

Patent OwnerAddress
ROCHE COLORADO CORPORATIONBOULDER TECHNOLOGY CENTER 2075 NORTH 55TH STREET BOULDER CO 80301

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Micheli, Roger P Louisville, CO 5 11
Nuiry, Ileana Isabel Boulder, CO 1 0

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