Adenovirus vectors containing cell status-specific response elements and methods of use thereof
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United States of America Patent
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Issued Date -
Aug 24, 2006
app pub date -
Aug 18, 2005
filing date -
Sep 10, 1998
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Abandoned
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Abstract
The present invention provides adenoviral vectors comprising cell status-specific transcriptional regulatory elements which confer cell status-specific transcriptional regulation on an adenoviral gene. A 'cell status' is generally a reversible physiological and/or environmental state. The invention further provides compositions and host cells comprising the vectors, as well as methods of using the vectors.
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