Solid dispersion of tacrolimus
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United States of America Patent
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Issued Date -
Aug 10, 2006
app pub date -
Jul 9, 2004
filing date -
Jul 9, 2003
priority date (Note) -
Abandoned
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Abstract
The present invention relates to the carrier of the solid dispersion of tacrolimus, which is prepared by using the solid surfactant having a property of HLB value higher than or equal to about 7. The surfactants carry out a function of a carrier and a function of a dissolution enhancer, simultaneously. As a result, the dissolution rate of tacrolimus is improved, and the oral absorbability and the bioavailability may be increased due to rapid drug release.
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