Hcv gene transgenic animal
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United States of America Patent
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Issued Date -
Aug 3, 2006
app pub date -
Sep 24, 2002
filing date -
Oct 30, 2001
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention provides a transgenic animal expressing the full-length human hepatitis C virus (HCV) for the purpose of constructing a system for screening for a remedy for human hepatitis C. The present invention is a transgenic hepatitis C model animal, which has the full-length DNA of the hepatitis C virus incorporated therein and can express the full-length HCV gene, and a method of generating a hepatitis C model animal carrying the full-length HCV gene, which comprises introducing a vector containing the full-length DNA of hepatitis C virus into an ES cell, and causing the ES cells to undergo ontogenesis in a pseudo-parent.
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