Multivalent T cell receptor complexes
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United States of America Patent
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Issued Date -
Jul 13, 2006
app pub date -
Dec 29, 2005
filing date -
May 19, 1998
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a synthetic multivalent T cell receptor complex for binding to a MHC-peptide complex, which multivalent T cell receptor complex comprises a plurality of T cell receptors specific for the MHC-peptide complex. It is preferred that the T cell receptors are refolded recombinant soluble T cell receptors. The synthetic multivalent T cell receptor complex can be used for delivering therapeutic agents or for detecting MHC-peptide complexes, and methods for such uses are also provided.
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