IMPROVED COX-2 INHIBITORY COMPOSITIONS AND THERAPEUTIC REGIMEN
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United States of America Patent
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Issued Date -
Jul 13, 2006
app pub date -
Jan 10, 2006
filing date -
Jan 11, 2005
priority date (Note) -
Abandoned
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Abstract
This invention provides improved COX-2 inhibitory compositions comprising a combination of a selective inhibitor of COX-2 and a prostacyclin promoter, especially an antioxidant of the type known as food extracts. The invention also provides a regimen treating a disease that is responsive to inhibition of cyclooxygenase-2, comprising administering to a patient suffering from such a disease the combination of the invention comprising a selective inhibitor of COX-2 and a prostacyclin promoter in amounts and at intervals effective to therapeutically inhibit COX-2 while maintaining a therapeutically significant level of prostacyclin production.
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