Cancer immunotherapy incorporating p53
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United States of America Patent
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Issued Date -
Jul 13, 2006
app pub date -
Nov 17, 2005
filing date -
Nov 17, 2004
priority date (Note) -
Abandoned
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Abstract
A method of stimulating an immune response to a tumor in an immunocompetent subject by administering a p53 expression construct to a tumor. The construct expresses p53 in tumor cells in an amount sufficient to stimulate an immune response against the tumor. Both viral and non-viral delivery systems are contemplated. The method can be combined with chemotherapy agents as well as with other cancer therapies.
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