Formulations useful against hepatitis C virus infections
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United States of America Patent
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N/A
Issued Date -
Jul 13, 2006
app pub date -
Dec 1, 2003
filing date -
Nov 29, 2002
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention relates generally to chemical compounds and substances which are effective against Hepatitis C virus (HCV) infections. Moreover, the present invention relates to compositions comprising said compounds and/or substances, to methods for preventing HCV infections as well use of the compounds and/or substances for the preparation of compositions useful for the prophylaxis and/or treatment of HCV infections. Useful compounds and substances according to the invention are selenium, selenium salts, Vitamin D.sub.3 and retinoids, like all trans retinoic acid and salts thereof, C.sub.1-C alkyl amides of all trans retinoic acid and salts thereof, C.sub.1-C.sub.10 alkyl esters of all trans retinoic acid and salts thereof, 9-cis retinoic acid and salts thereof, C.sub.1-C.sub.10 alkyl amides of 9-cis retinoic acid and salts thereof, C.sub.1-C.sub.10 alkyl esters of 9-cis retinoic acid and salts thereof, (E)-4-[2(5,6,7,8-tetrahydro-5,5,8,8-tetra methyl-2-naphthalenyl-1-propenyl)benzoic acid (TTNPB), (4-[5,6,7,8-tetrahydro5,5,8,8-tetramethyl-2-naphthalenyl)carboxamido]benz-oic acid (AM-580), N-(4-hydroxyphenyl)retinamide (4-HPR), and 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (AHPN).
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