Use of cis-epoxyeicosantrienoic acids and inhibitors of soluble epoxide hydrolase to reduce damage from stroke
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United States of America Patent
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Issued Date -
Jul 6, 2006
app pub date -
Sep 23, 2005
filing date -
Sep 23, 2004
priority date (Note) -
Abandoned
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Abstract
The invention provides uses and methods for reducing brain damage from stroke. The uses comprise the use of an inhibitor of soluble epoxide hydrolase (sEH) for the manufacture of a medicament to reduce brain damage from stroke, as well as the use of cis-epoxyeicosatrienoic acid (EET) for that purpose. The methods comprise the administration of sEH inhibitors to persons who have had a stroke, or who are at risk of having a stroke. Optionally, the methods also include the administration of EETs.
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