Use of a gene mutation in the human gnas gene for predicting risks of diseases, courses of the disease and for predicting the response to disease therapies
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United States of America Patent
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Issued Date -
Jul 6, 2006
app pub date -
Feb 19, 2004
filing date -
Feb 19, 2003
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Abandoned
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Abstract
The invention concerns the use of a genomic gene modification in the gene for the Gas subunit of the human G protein, coded by the gene GNAS (or GNAS1), for the prediction of disease risks, disease clinical courses and responses to pharmacological and non-pharmacological measures and for the prediction of adverse drug reactions (side-effects). In addition, it concerns the provision of individual gene modifications and haplotypes, with the help of which additional gene modifications applicable for the above purposes can be detected and validated.
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