HMG-CoA reductase inhibitor extended release formulation

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United States of America Patent

SERIAL NO

11355771

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Abstract

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Controlled release oral solid dosage form for the reduction of serum cholesterol levels in humans include a drug comprising an alkyl ester of hydroxy substituted naphthalenes (e.g., lovastatin) and a controlled release carrier, such that the dosage form provides a mean time to maximum plasma concentration (T.sub.max) of the drug which occurs at about 10 to about 32 hours after oral administration on a once-a-day basis to human patients. The dosage form provides a therapeutically effective reduction in serum cholesterol levels. Methods of reducing serum cholesterol levels in humans are also disclosed.

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Patent Owner(s)

Patent OwnerAddress
ANDRX LABS LLCDAVIE FL 33314

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Chih-Ming Davie, FL 467 5678
Chou, Joseph Coral Springs, FL 38 1207
Wong, David Hollywood, FL 159 3078

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