Formulations of bisphosphonate drugs with improved bioavailability
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United States of America Patent
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Issued Date -
Jun 22, 2006
app pub date -
Dec 16, 2004
filing date -
Dec 16, 2004
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Abstract
This invention relates to formulations of bisphosphonates such as alendronate. The formulations taught herein enhance bioavailability of bisphosphonates and reduce esophageal and gastric ulcerations associated with them. Also taught herein are methods of preparing the formulations and their clinical use in the treatment of osteoporosis and other bone diseases.
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