Method and apparatus for washing solid substrate with ultrasonic wave after hybridization reaction

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United States of America Patent

APP PUB NO 20060124152A1
SERIAL NO

10524903

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Abstract

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A method and apparatus for washing solid substrate with ultrasonic wave after hybridization reaction are provided. The method includes (1) putting the solid substrate into a container having a washing solution, on which the hybridization reaction has been completed, (2) using an ultrasonic generator to produce a certain strength of ultrasonic wave and transmit it into the washing solution, (3) washing the substrate by means of the cavitation effect being produced in the washing solution by the ultrasonic wave. Since the cavitation bubbles in the washing solution can produce intensive efflux and local microslipstream against the solid surface, evidently reducing the liquid surface tension and friction and enhance the liquid flow, non-specific adsorbate and deposit bound weakly on the solid substrate can be washed down rapidly.

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Patent Owner(s)

Patent OwnerAddress
TSINGHUA UNIVERSITY100084 NO 1 TSINGHUA YUAN BEIJING HAIDIAN DISTRICT BEIJING CITY BEIJING CITY 100084
CAPITALBIO CORPORATIONCHANGPING DISTRICT BEIJING 102206

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cheng, Jing Beijing, CN 184 3034
Guo, Min Beijing, CN 70 558
Li, Gang Beijing, CN 629 4192
Wu, Ruige Beijing, CN 6 6
Xing, Wanli Beijing, CN 40 155

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