Cyanomethyl derivatives as cysteine protease inhibitors

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United States of America Patent

APP PUB NO 20060122184A1
SERIAL NO

10536889

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention is directed to cyanomethyl derivatives that are inhibitors of cysteine protease, in particular, cathepsin B, K, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.

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Patent Owner(s)

Patent OwnerAddress
AXYS PHARMACEUTICALS INC180 KIMBALL WAY SO SAN FRANCISCO CA 94080

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Graupe, Michael Pacifica, CA 108 1312
Lau, Agnes San Francisco, CA 2 1
Link, John O San Francisco, CA 143 1969
Liu, Yang Foster City, CA 1941 7962
Mossman, Craig J Campbell, CA 10 30
Patterson, John W Mountain View, CA 38 411
Zipfel, Sheila M Mountain View, CA 33 170

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