Substituted carboxylic acids
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United States of America Patent
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Issued Date -
May 4, 2006
app pub date -
Oct 28, 2005
filing date -
Oct 28, 2004
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Abandoned
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Abstract
The present invention relates to compounds and pharmaceutically acceptable salts of formula I: which are useful in the treatment of metabolic disorders related to insulin resistance or hyperglycemia. These compounds include inhibitors of protein tyrosine phosphatase (PTP-1B) that are useful in the treatment of diabetes and other PTP-1B mediated diseases, such as cancer, neurodegenerative diseases and the like. The compounds of the invention are also useful in pharmaceutical compositions and methods of treating the aforementioned conditions.
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