Thermosensitive and biocompatible amphiphilic cyclic phosphazene trimer and preparation method thereof
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United States of America Patent
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Issued Date -
Apr 20, 2006
app pub date -
Oct 14, 2005
filing date -
Oct 19, 2004
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Abandoned
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Abstract
The present invention relates to a thermosensitive and biocompatible poly(organophosphazenes) represented by Formula 1, and a preparation method thereof: wherein x is an integer of 3, 4, 7, 12 or 16; R is methyl, ethyl or benzyl group; R.sup.1 is selected from the group consisting of CH.sub.2CH(CH.sub.3).sub.2, CH.sub.2C.sub.6H.sub.5, CH(CH.sub.3)CH.sub.2CH.sub.3 and CH.sub.3; R.sup.2 is selected from the group consisting of CH.sub.2COOR, CH.sub.2CH.sub.2COOR, CH.sub.2CH(CH.sub.3).sub.2 and CH(CH.sub.3)CH.sub.2CH.sub.3; R.sup.3 and R.sup.4 are independently selected from the group consisting of CH.sub.2COOR, CH.sub.2CH.sub.2COOR and H, wherein said R is the same as defined above; a, b and c are equal to 1, respectively; and d and e are 0 or 1.
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