Genetic predictor of efficacy of anti-asthmatic agents for improving pulmonary function

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United States of America Patent

APP PUB NO 20060069074A1
SERIAL NO

11176026

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to methods for determining and predicting the efficacy of therapeutics for the treatment of an individual with asthma based on that individual's .beta..sub.2-adrenergic receptor. The invention finds particular applicability to the treatment of an individual with asthma with an inhaled corticosteroid or a leukotriene receptor antagonist who is homozygous for arginine at position 16 of the .beta..sub.2-adrenergic receptor.

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Patent Owner(s)

Patent OwnerAddress
THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA220 W SIXTH STREET 4TH FLOOR TUCSON AS 85701

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bacharier, Leonard B Town & Country, MO 1 0
Bloomberg, Gordon R St. Louis, MO 1 0
Chinchilli, Vernon M Elizabethtown, PA 2 57
Guilbert, Theresa W Tucson, AZ 1 0
Heldt, Gregory P US 1 0
Klimecki, Walter T Vail, AZ 1 0
Larsen, Gary L Littleton, CO 1 0
Lemanske, Robert F JR Madison, WI 1 0
Liu, Wenlei Palmyra, PA 1 0
Martinez, Fernando D Tucson, AZ 1 0
Morgan, Wayne J Tucson, AZ 1 0
Phillips, Brenda Elizabethtown, PA 2 17
Sorkness, Christine A Madison, WI 1 0
Spahn, Joseph D Denver, CO 2 1
Strunk, Robert C St. Louis, MO 1 0
Szefler, Stanley J Aurora, CO 2 1
Taussig, Lynn M Greenwood Village, CO 3 46
Zeiger, Robert S San Diego, CA 1 0

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