Mobile phase treatment for chromatography

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United States of America Patent

APP PUB NO 20060054558A1
SERIAL NO

10505289

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A convenient and efficient method for heating or cooling the mobile phase fluid of a chromatographic system prior to its entry into the chromatographic column is described. The 'preheating' or 'precooling' process is carried out using an apparatus containing a short length of tubing where the mobile phase is heated or cooled. The heating or cooling is performed using a heating or cooling element that is in intimate thermal contact with the exterior of the tubing. The temperature change of the mobile phase is measured downstream by a non-invasive, low-mass sensing element on the exterior of the tubing. With a low mass heating or cooling element, the device can be very responsive and allows for rapid equilibration and convenient temperature programming of the mobile phase. This configuration also requires only a short mobile phase contact time, is non-invasive, adds no dead volume, and allows for use of columns over a wide range of internal diameter, flow rates and temperatures.

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Patent Owner(s)

Patent OwnerAddress
SELERITY TECHNOLOGIES INC2484 WEST CUSTER ROAD SALT LAKE CITY UT 84104

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jones, Brian South Jordan, UT 160 3585
Porter, NathanL Kaysville, UT 1 16

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