Cytotoxic nucleoside analog compound 003 for treating cancer
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United States of America Patent
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Issued Date -
Mar 2, 2006
app pub date -
Aug 31, 2005
filing date -
Aug 31, 2004
priority date (Note) -
Abandoned
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Abstract
The present invention provides pharmaceutical compositions comprising Compound 003 or metabolites thereof in combination with one or more carboxylesterase inhibitors. The invention provides methods for inhibiting cellular proliferation associated with proliferative cell disorders in a subject by administering Compound 003 or metabolites thereof. The invention also provides methods for arresting the cell cycle. Methods of inhibiting proliferation of cells for treatment of cancer by administering Compound 003 are described.
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