Process for producing paroxetine hydrochloride hydrate
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United States of America Patent
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Issued Date -
Feb 23, 2006
app pub date -
Sep 17, 2003
filing date -
Sep 19, 2002
priority date (Note) -
Abandoned
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Abstract
A process for preparing a paroxetine hydrochloride hydrate, comprising reacting (3S, 4R)-1-tert-butoxycarbonyl-4-(4-fluorophenyl)-3-[(3,4-methyl-ene-dioxy)phenoxymethyl]piperidine with hydrogen chloride in the presence of water, and allowing crystals to separate out from the resulting reaction mixture in the presence of water.
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