Anti-GPE antibodies, their uses and assays for weakly immunogenic molecules
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United States of America Patent
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app pub date -
Oct 22, 2004
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Mar 16, 2001
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Abstract
Anti-GPE antibodies are provided that can be used to detect the presence of GPE in a sample. GPE antibodies can be raised against conjugated GPE to produce antibodies that are specific for a GPE that has been derivatized using a similar coupling chemistry as was used for making the GPE conjugate. To detect GPE in a sample, the sample is exposed to a derivatizing agent to produce a derivatized GPE that is recognized by the anti-GPE antibody. Using similar strategies, antibodies can be raised against other weakly immunogenic molecules (WIMs) that can be the basis for assays and kits for assaying for WIMs.
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