Controlled modulation of the pharmacokinetics and biodistribution of aptamer therapeutics

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United States of America Patent

APP PUB NO 20060030535A1
SERIAL NO

11075648

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Abstract

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Materials and methods are provided to modulate, in a controlled manner, the pharmacokinetic and biodistribution properties of nucleic acid aptamers, and to enhance their safety and efficacy properties as therapeutic agents.

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Patent Owner(s)

Patent OwnerAddress
ARCHEMIX CORP300 THIRD STREET FIRST FLOOR CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Healy, Judith M Lexington, MA 6 27
Kurz, Markus Newton, MA 39 729
Margolskee, Dorothy J Upper Montclair, NJ 1 19
McCauley, Thomas Greene Cambridge, MA 18 187
Thompson, Kristin Arlington, MA 13 341
Wilson, Charles Concord, MA 82 1076

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