Treatment of viral encephalitis by agents blocking alpha-VLA-4 integrin function
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United States of America Patent
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Issued Date -
Feb 9, 2006
app pub date -
Dec 16, 2004
filing date -
Jan 21, 1998
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Abandoned
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Abstract
The invention provides methods of treating viral encephalitis in a patient. Such methods entail administering to the patient an effect amount of an agent that inhibits binding of leukocytes to brain endothelial cells via leukocyte surface antigen alpha-4 integrin. Such agents include antibodies and small molecules that specially bind to alpha-4 integrin.
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