Materials and methods for identifying anti-schizophrenic agents
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United States of America Patent
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Issued Date -
Feb 9, 2006
app pub date -
Aug 6, 2004
filing date -
Aug 6, 2004
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Abandoned
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Abstract
The invention relates to materials and methods of identifying modulators of N-methyl-D-Aspartate (NMDA) receptor phosphorylation and function, including anti-schizophrenic agents that modulate NMDA receptor function. The methods of the invention utilize animal models of schizophrenia and cell-based assays to identify modulators of NMDA function. The invention further provides anti-schizophrenic agents identified by these methods. The invention relates to methods of treating schizophrenia using the modulators and anti-schizophrenic agents identified by the methods of the invention.
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