Heteroclitic analogs and related methods
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United States of America Patent
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app pub date -
Apr 7, 2003
filing date -
Apr 5, 2002
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Abstract
Heteroclitic analogs of class I epitopes are prepared by providing conservative, semi-conservative, or non-conservative amino acid substitutions at positions 3 and/or 4 and/or 5 and/or 6 and/or 7 and/or 8 and/or 9 and/or 10 of these epitopes. The analogs are useful in eliciting immune responses with respect to the corresponding wild-type epitopes.
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