Novel physiologically active substances
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United States of America Patent
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Issued Date -
Jan 12, 2006
app pub date -
May 29, 2003
filing date -
May 29, 2002
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a compound represented by the formula (I): (wherein, R.sup.3, R.sup.6, R.sup.7 and R.sup.21 are the same as or different from one another and each represents a hydroxyl group etc.), a pharmacologically acceptable salt thereof or a hydrate of them. The compound (I) of the present invention suppresses angiogenesis, in particular, suppresses VEGF production in a hypoxic condition and is useful as a therapeutic agent for treating solid cancer.
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