Pharmaceutical compositions comprising NEP-inhibitors, inhibitors of the endogenous endothelin producing system and AT1 receptor antagonists

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United States of America Patent

APP PUB NO 20050288272A1
SERIAL NO

11155782

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Abstract

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A combination therapy for cardiovascular diseases, in particular essential hypertension, pulmonary hypertension and/or congestive heart failure, involving administering a synergistic combination of at least one inhibitor of neutral endopeptidase, at least one inhibitor of the endogenous endothelin producing system, and at least one AT.sub.1 receptor antagonist.

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Patent Owner(s)

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SOLVAY PHARMACEUTICALS GMBHHANS-BOECKLER-ALLEE 20 D-30173 HANNOVER

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fischer, Yvan Barsinghausen, DE 15 47
Hoeltje, Dagmar US 15 145
Straub, Matthias Barsinghausen, DE 10 11
Thormaehlen, Dirk Ronnenberg, DE 11 149
Witte, Klaus Hannover, DE 18 87
Ziegler, Dieter Hemmingen, DE 33 156

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