Colchinol derivatives as vascular damaging agents
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United States of America Patent
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Issued Date -
Dec 15, 2005
app pub date -
Jan 6, 2003
filing date -
Jul 7, 2000
priority date (Note) -
Abandoned
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Abstract
The invention relates to colchinol derivatives of the formula 1: wherein the substituents are as defined in the description or a pharmaceutically-acceptable salt, solvate or pro-drug thereof. The invention also relates to processes for preparing compounds of formula (1), pharmaceutical compositions of compounds of formula (1) and the use of compounds of formula (1), in the manufacture of a medicament for use in the production of a vascular damaging effect in a warm blooded animal.
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