Magnetic device for isolation of cells and biomolecules in a microfluidic environment
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United States of America Patent
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Issued Date -
Dec 1, 2005
app pub date -
Mar 3, 2005
filing date -
Mar 3, 2004
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Abstract
The present invention features a new and useful magnetic device and methods of its use for isolation, enrichment, and purification of cells, proteins, DNA, and other molecules. In general the device includes magnetic regions or obstacles to which magnetic particles can bind. The chemical groups, i.e., capture moieties, on the surface of the magnetic particles may then be used to bind particles, e.g., cells, or molecules of interest from complex samples, and the bound species may then be selectively released for downstream collection or further analysis.
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