Method for gene mapping from genotype and phenotype data
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United States of America Patent
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Issued Date -
Nov 10, 2005
app pub date -
May 10, 2005
filing date -
Apr 4, 2002
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Abstract
A method for gene mapping from genotype and phenotype data utilizes linkage disequilibrium between genetic markers mi, which are polymorphic nucleic acid or protein sequences or strings of single-nucleotide polymorphisms deriving from a chromosomal region. All marker patterns P that satisfy a certain pattern evaluation function e(P) are searched from the data, each marker mi of the data is scored by a marker score and the location of the gene is predicted as a function of the scores s(mi) of all the markers mi in the data.
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