Composition for treatment of and method of monitoring hepatitis C virus using interferon-tau
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United States of America Patent
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Issued Date -
Nov 3, 2005
app pub date -
Jul 7, 2005
filing date -
Jul 19, 2000
priority date (Note) -
Abandoned
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Abstract
A method of monitoring treatment of HCV by oral administration of ovine IFN-.tau. is disclosed. The method includes measuring the blood levels of 2',5'-oligoadenylate synthetase prior to and after such oral administration, and if necessary, adjusting the dose of IFN-.tau. until a measurable increase in blood 2',5'-oligoadenylate synthetase level, relative to the level observed prior to administration, is observed. Also disclosed are oral-delivery compositions for use in treating HCV in an HCV-infected patient comprising ovine IFN-.tau., in a dosage effective to stimulate bloodstream levels of 2',5'-oligoadenylate synthetase.
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