Automated sequential injection analysis systems for the determination of trace endotoxin levels

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United States of America Patent

APP PUB NO 20050244299A1
SERIAL NO

10512888

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Abstract

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A method used to detect endotoxin uses a system (10) having bidirectional pump (20), multiport valve (30), fluid section valve (170), fluid holding member (50), solenoid valve (60), air source (63) and detector (100). Sample, LAL reagent and chromogenic substrate fluid segments are introduced into the holding member (50) between air segments, the reagents are then mixed and introduced into the detector (100) for measurement The system can be washed with an alkaline solution and followed by cthanol, or washed with tricthylaminc followed by water.

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Patent Owner(s)

Patent OwnerAddress
CAMBREX BIO SCIENCE WALKERSVILLE INC8830 BIGGS FORD ROAD WALKERSVILLE MD 21793-0127

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Berzofsky, Ronald Norman Timonium, MD 2 25
Bonen, Matthew Richard New Market, MD 1 15
Dasgupta, Purnendu Kumar Lubbock, TX 3 52

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